自然-生物技术杂志报告:糖尿病的干细胞研究取得了突破

上一篇 / 下一篇  2008-02-23 23:11:19 / 个人分类:uk dm

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Scientists claim they are a step closer to finding a cure for diabetes as they have converted stem cells from a human embryo into insulin-producing cells.

The study, published in Nature Biotechnology, said researchers converted the stem cells into immature 'beta' cells and injected them into mice. Within one to three months, the cells developed into fully functioning insulin-producing cells.

The transplanted cells regulated the blood glucose levels of mice whose own insulin-producing cells had been destroyed to mimic some forms of diabetes.

Another Step Forward

 

Dr Iain Frame, Director of Research at Diabetes UK says: “This research is based on a mouse model of diabetes which relies on chemicals to destroy the islet cells. This is very different to what happens in people with Type 1 diabetes, where the immune system mounts a complex attack against the beta cells. 

“The researchers have not produced fully functioning islet cells, just the insulin producing beta cells. We would certainly not wish to raise people's expectations that this research is a major leap forward in diabetes research, but it does provide another step forward in our knowledge. 
 
“Although stem cell research is very much in its infancy, Diabetes UK believes it offers a real possibility of leading to a cure for diabetes.”

 

 


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wzj3190发布于2008-02-24 00:11:36
英文看不懂!请大侠翻译一下,分享喜讯……
rockytime的个人空间 rockytime 发布于2008-02-24 01:11:15
大意就是说,在小白鼠身上取得了成功。只是更接近而已……
我要上学发布于2008-02-29 21:25:34
我来试着翻译一下
科学家称, 他们将从人的胚胎中提取的干细胞成功转化为可以制造胰岛素的细胞,在研究治愈糖尿病方面又前进了一步。
       这项研究发表于自然生物技术杂志上,研究人员将干细胞转化为未成熟的 B-细胞,并将其注入大鼠体内, 一到三个月后, 这些细胞成长为具有完整功能的制造胰岛素的细胞。
      这些移植的细胞能够调节大鼠的血糖水平。为了模拟糖尿病,在进行研究之前,这些大鼠的制造胰岛素的细胞已被人为地加以破坏。
   
       上述做法是用化学试剂来破坏胰岛细胞,这并不能完全模拟 DM1 型患者的发病机理 (免疫系统攻击人的 B-细胞)。研究人员只是培育出了制造胰岛素的细胞,并未培养出具有完全功能的胰岛细胞。我们希望读者不要把这项研究结果当作糖尿病研究的一次质的飞跃,只是我们对这方面更多了一些理解。
       尽管干细胞研究还很不成熟,但这项研究的确为治愈糖尿病提供了一种真实的可能性。
dozber发布于2008-04-20 20:37:18
就是不知道目前国外研究到什么程度了,有知道的吗?
我来说两句

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